Destination Image of Himachal Pradesh: Foreign Tourist Perception

Destination Image is a psychological set of emotions in a tourist’s mind. This study is aninquiry from 384 Foreign Nationals who included destination Himachal in their visit toIndia. The latent factors of ‘destination image’ were extracted and validated throughstructural equation modeling (SEM). Out of the ten explored latent factors ‘affective’dimension is the major element followed by ‘infrastructure’, ‘culture’ and ‘safety’ are actingas significant persuading forces in destination image formation. The study will help variousorganizations and agencies to position their tourism products. Future researchers caninvestigate the change in destination image with other locations having the samegeographical conditions. This study is limited to the present experience of tourists anddidn’t include the revisit experiences of foreign tourists

DPP-IV Inhibitors from natural sources: An alternative approach for treatment and management of diabetes

Diabetes is a chronic metabolic disorder present in almost all countries. According to WHO, T2DM is the World’s fifth leading cause of death. Treatment for T2DM depends on the incretin hormone (GLP-1 & GIP). GLP-1 plays a vital role in the body’s metabolism, such as insulin secretion but DPP-IV enzyme inactivates these incretin hormones. Therefore, it becomes important to identify DPP-IV inhibitors that act as prospective antidiabetic agents. Synthetic inhibitors like vildagliptin, sitagliptin, and saxagliptin are available in the market but they have some undesirable side effects. There are several natural plants as well as products that provide safe and effective medication against diabetes by DPP-IV enzyme inhibitory mechanism. This review summarizes recent advancement of DPP-IV inhibitors from medicinal plants and isolated phytoconstituents including alkaloids, flavonoids, terpenoids, phenol, and stilbenoids which are responsible for the DPP-IV inhibition

DPP-IV Inhibitors from natural sources: An alternative approach for treatment and management of diabetes

227-237Diabetes is a chronic metabolic disorder present in almost all countries. According to WHO, T2DM is the World’s fifth leading cause of death. Treatment for T2DM depends on the incretin hormone (GLP-1 & GIP). GLP-1 plays a vital role in the body’s metabolism, such as insulin secretion but DPP-IV enzyme inactivates these incretin hormones. Therefore, it becomes important to identify DPP-IV inhibitors that act as prospective antidiabetic agents. Synthetic inhibitors like vildagliptin, sitagliptin, and saxagliptin are available in the market but they have some undesirable side effects. There are several natural plants as well as products that provide safe and effective medication against diabetes by DPP-IV enzyme inhibitory mechanism. This review summarizes recent advancement of DPP-IV inhibitors from medicinal plants and isolated phytoconstituents including alkaloids, flavonoids, terpenoids, phenol, and stilbenoids which are responsible for the DPP-IV inhibition

Upgraded Ultrasonic Animal Deterrent Device

In this research work, an up-gradation to the pre-existing technology utilizing ultrasound has been proposed to deter animals. Establishing a low input voltage and maintaining a desired operating distance range has been prioritized along with retaining an effective range of random frequency operating on a wide bandwidth region. It ensures a long run of operation by consuming only a little amount of energy that can be substantially achieved from solar energy and alternatively from main power in the absence of solar energy

Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines

Xylazine (1.1 mg/kg), butorphanol (0.02 mg/kg), guaifenesin 5% (20 mg/kg), and ketamine (2.2 mg/kg) combinations were able to induce short-term surgical anaesthesia for 23.33 ± 2.57 min in Spiti ponies with excellent to good muscle relaxation and analgesia. Urination and neighing was a constant feature during recovery period. Biphasic P wave, biphasic T wave, and depressed PR segment were common electrocardiographic findings. Biochemical attributes were within physiological limits except a significant increase in ALT values during anaesthesia. The values returned to normal during recovery ruling out any renal or hepatic toxicity. Occasionally, negative T wave, notched P wave, and sinus block were noticed. It is recommended that the anaesthetic combinations xylazine-butorphanol-guaifenesin-ketamine can be safely used for short-term total intravenous anaesthesia (TIVA) in equines under field conditions